Publications

Below are a selection of publications from the Biopharmaceutical Formulation Group.

Publications

A Taylor Dispersion Analysis Method for the Sizing of Therapeutic Proteins and Their Aggregates Using Nanolitre Sample Quantities Wendy Hulse, Robert T Forbes International Journal of Pharmaceutics 416 (2011) p394-397 

Taylor Dispersion Anlaysis Compared to Dynamic Light Scattering for The Size Analysis of Therapeutic Peptides and Proteins and Their Aggregates Andrea Hawe, Wendy L. Hulse, Wim Jiskoot, Robert T. Forbes Pharm Res  28(9) (2011) p2302-2310

A nanolitre method to determine the hydrodynamic radius of proteins and small molecules by Taylor dispersion analysis Wendy L. Hulse and Robert T. Forbes International Journal of Pharmaceutics 411 (2011) p64-68

Influence of Protein on Mannitol Polymorphic Form Produced During Co-Spray Drying Wendy L. Hulse, Robert T. Forbes, Micheal C. Bonner, Mathias Getrost International Journal of Pharmaceutics 382 (2009) p67-72

The Characterisation and Comparison of Spray Dried Mannitol Wendy L. Hulse, Robert T. Forbes, Micheal C. Bonner, Mathias Getrost Drug Development and Industrial Pharmacy 35(36) (2009) p712-718

Do Co-Spray Dried Excipients Offer Better Lysozyme Stabilisation than Single Excipinets W.L. Hulse, R.T. Forbes M.C. Bonner Eur. J. Pharm Sci., 33 (2008) p294-305

The Impact of Low Level Inorganic Impurities on Key Physicochemical Properties of Paracetamol . W.L.Hulse, M. De Matas, I.M.Grimsey Int. J.Pharm., 349 (2008) p61-65

Posters and Presentations

AAPS Washington 2011

Advances in Taylor Dispersion Analysis AAPS 2011

Taylor Dispersion Analysis to Gain an Insight into Formulation Buffer Salts

TDA to Gain an Insight into Inter Batch Variability of Protein Aggregation

Advances in Dissolution Imaging AAPS 2011

Influence of Surface Properties AAPS 2011

PEPCON Beijing 2011

Advances in Taylor Dispersion Analysis

AAPS New Orleans 2010

Use of Taylor Dispersion to Gain an Insight into the Reversibility of Protein

Use of a Novel Dissolution Imaging System (PDF)

Use of Material Generated Moisture Profiling to Probe Physical Form Change (PDF)

Effect of a Polymeric Vehicle on Co-crystal Formation Within Cast Films (PDF)

EUFEPS Nice 2009

Introduction to Taylor Dispersion Analysis.